error - readline() on closed filehandle IN at /share/pkg.7/metabolic/4.0/install//METABOLIC/METABOLIC-G.pl line 1147.

[isuvodeep]

I am running metabolic G on some nitrogen-cycling organisms.
I am getting this error repeatedly>
readline() on closed filehandle IN at /share/pkg.7/metabolic/4.0/install//METABOLIC/METABOLIC-G.pl line 1147.

I tried earlier where it was running the hmm even after this line, but when I have a larger number of genomes (~3500), it's always showing this line.

Is it a problem when I have a large number of genomes? Or is it because of some specific error ?

Thanks in advance for your help.