diff --git a/conf/requirements.txt b/conf/requirements.txt
index a16372b7..12e8bbda 100644
--- a/conf/requirements.txt
+++ b/conf/requirements.txt
@@ -1,4 +1,4 @@
-wheel==0.37.1
+wheel==0.46.2
 asn1crypto==1.5.0
 bcrypt==4.0.1
 biopython==1.79