diff --git a/packages/opentelemetry-instrumentation-google-generativeai/opentelemetry/instrumentation/google_generativeai/config.py b/packages/opentelemetry-instrumentation-google-generativeai/opentelemetry/instrumentation/google_generativeai/config.py
index 93ad99eb9f..f2bdc056f5 100644
--- a/packages/opentelemetry-instrumentation-google-generativeai/opentelemetry/instrumentation/google_generativeai/config.py
+++ b/packages/opentelemetry-instrumentation-google-generativeai/opentelemetry/instrumentation/google_generativeai/config.py
@@ -1,9 +1,10 @@
-from typing import Callable
+from typing import Callable, Optional
 
 
 class Config:
     exception_logger = None
     use_legacy_attributes = True
-    upload_base64_image: Callable[[str, str, str, str], str] = (
-        lambda trace_id, span_id, image_name, base64_string: str
-    )
+    # Set by instrumentor only when a real image uploader is provided (e.g.,
+    # Traceloop cloud).  None by default — image processing is skipped when no
+    # uploader is configured, avoiding KeyError on non-Traceloop endpoints.
+    upload_base64_image: Optional[Callable[[str, str, str, str], str]] = None
diff --git a/packages/opentelemetry-instrumentation-openai/opentelemetry/instrumentation/openai/shared/config.py b/packages/opentelemetry-instrumentation-openai/opentelemetry/instrumentation/openai/shared/config.py
index 088a9a8f8a..8c30171b0d 100644
--- a/packages/opentelemetry-instrumentation-openai/opentelemetry/instrumentation/openai/shared/config.py
+++ b/packages/opentelemetry-instrumentation-openai/opentelemetry/instrumentation/openai/shared/config.py
@@ -7,9 +7,7 @@ class Config:
     enrich_assistant = False
     exception_logger = None
     get_common_metrics_attributes: Callable[[], dict] = lambda: {}
-    upload_base64_image: Callable[[str, str, str, str], str] = (
-        lambda trace_id, span_id, image_name, base64_string: str
-    )
+    upload_base64_image: Optional[Callable[[str, str, str, str], str]] = None
     enable_trace_context_propagation: bool = True
     use_legacy_attributes = True
     event_logger: Optional[Logger] = None
diff --git a/packages/opentelemetry-instrumentation-vertexai/opentelemetry/instrumentation/vertexai/config.py b/packages/opentelemetry-instrumentation-vertexai/opentelemetry/instrumentation/vertexai/config.py
index 93ad99eb9f..e08814f50f 100644
--- a/packages/opentelemetry-instrumentation-vertexai/opentelemetry/instrumentation/vertexai/config.py
+++ b/packages/opentelemetry-instrumentation-vertexai/opentelemetry/instrumentation/vertexai/config.py
@@ -1,9 +1,7 @@
-from typing import Callable
+from typing import Callable, Optional
 
 
 class Config:
     exception_logger = None
     use_legacy_attributes = True
-    upload_base64_image: Callable[[str, str, str, str], str] = (
-        lambda trace_id, span_id, image_name, base64_string: str
-    )
+    upload_base64_image: Optional[Callable[[str, str, str, str], str]] = None
diff --git a/packages/traceloop-sdk/traceloop/sdk/__init__.py b/packages/traceloop-sdk/traceloop/sdk/__init__.py
index 22bf97d5c2..0fefa42d05 100644
--- a/packages/traceloop-sdk/traceloop/sdk/__init__.py
+++ b/packages/traceloop-sdk/traceloop/sdk/__init__.py
@@ -146,7 +146,9 @@ def init(
             exporter=exporter,
             sampler=sampler,
             should_enrich_metrics=should_enrich_metrics,
-            image_uploader=image_uploader or ImageUploader(api_endpoint, api_key),
+            image_uploader=image_uploader or (
+                ImageUploader(api_endpoint, api_key) if endpoint_is_traceloop else None
+            ),
             instruments=instruments,
             block_instruments=block_instruments,
             span_postprocess_callback=span_postprocess_callback,
diff --git a/packages/traceloop-sdk/traceloop/sdk/tracing/tracing.py b/packages/traceloop-sdk/traceloop/sdk/tracing/tracing.py
index dc469911e0..b758a928cd 100644
--- a/packages/traceloop-sdk/traceloop/sdk/tracing/tracing.py
+++ b/packages/traceloop-sdk/traceloop/sdk/tracing/tracing.py
@@ -163,7 +163,7 @@ def chained_on_start(span, parent_context=None, orig=original_on_start):
 
             init_instrumentations(
                 should_enrich_metrics,
-                image_uploader.aupload_base64_image,
+                image_uploader.aupload_base64_image if image_uploader else None,
                 instruments,
                 block_instruments,
             )