Hi, We are trying to apply your RWR imputation method on single cell hic data with 10kb resolution. I see the rwr output included each .bedpe file for each chromosome of all single cell, even though we specifically provided input files only for chromosome 22. This has raised a question about how imputation is performed on other chromosomes.
Could you kindly provide some clarification on the following points:
Chromosome-Specific Imputation: Why does the RWR output contain .bedpe files for all chromosomes, even when the input is limited to chromosome 22?
Input Requirement: Is it necessary for the input to include data for all chromosomes for each single cell? Can we impute for a specific one chromosome?
Thank you
Hi, We are trying to apply your RWR imputation method on single cell hic data with 10kb resolution. I see the rwr output included each .bedpe file for each chromosome of all single cell, even though we specifically provided input files only for chromosome 22. This has raised a question about how imputation is performed on other chromosomes.
Could you kindly provide some clarification on the following points:
Chromosome-Specific Imputation: Why does the RWR output contain .bedpe files for all chromosomes, even when the input is limited to chromosome 22?
Input Requirement: Is it necessary for the input to include data for all chromosomes for each single cell? Can we impute for a specific one chromosome?
Thank you