diff --git a/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements.txt b/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements.txt
index 197c50c05d..2ef29b962d 100644
--- a/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements.txt
+++ b/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements.txt
@@ -1,4 +1,4 @@
-setuptools==36.5.0
+setuptools==65.5.1
 cwl-runner
 cwltool==1.0.20180403145700
 schema-salad==2.7.20180514132321
diff --git a/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements3.txt b/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements3.txt
index 021b835021..cb904cecc9 100644
--- a/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements3.txt
+++ b/dockstore-webservice/src/main/resources/requirements/1.5.0/requirements3.txt
@@ -1,4 +1,4 @@
-setuptools==36.5.0
+setuptools==65.5.1
 cwl-runner
 cwltool==1.0.20170828135420
 schema-salad==2.6.20170806163416