README.md

Gout_GWAS_Code

Repository for all the codes written for gout GWAS meta-analysis and all other analyses that used the meta-analysis results.

Meta-analysis scripts

Contain all scripts relevant to the QC, single-ancestry and trans-ancestry meta-analysis.

Summary statistics for AFR, EAS, EUR, LAT, and TAMA are available on GWAS catalog with the accession IDs GCST90428594-GCST90428605.

Note that these summary statistics do not include the 23andMe data due to prior data use agreement with 23andMe.

Refer to the relevant README files in the directory.

Functional analysis scripts

Contain all scripts used for the downstream analyses that used the GWAS summary statistics from the meta-analysis.

Each analysis is split into separate directory:

• abc_scripts
• chip_scripts
• cojo_scripts
• colocalisation_scripts
• cytokine_qtl
• finemapping_scripts
• gene_prioritisation
• genetic_correlation
• heterogeneity
• ldsc_scripts
• loci_identification
• lz_manhattan
• magma_scripts
• pathway_enrichment
• power_calculation
• prs_scripts
• tfbs_enrichment
• variant_annotation

Refer to the relevant README files in the directory.