Skip to content

README.md

Latest commit

 

History

History
30 lines (16 loc) · 1.43 KB

README.md

File metadata and controls

30 lines (16 loc) · 1.43 KB

Tutorials

A collection of Jupyter notebooks for using OpenMendel packages.

  • PLINK binary data input, summary statistics, filtering, and visualization. [ipynb]

  • Kinship calculation and comparison. [ipynb]

  • Population GWAS. [ipynb]

  • Iterative hard thresholding (IHT) for GWAS. [ipynb]

  • Heritability estimation. [ipynb]

  • GWAS based on linear mixed model. [ipynb]

  • SNP-set testing. [ipynb]

Citation

If you use OpenMendel analysis packages in your research, please cite the following reference in the resulting publications:

OPENMENDEL: a cooperative programming project for statistical genetics. Zhou H, Sinsheimer JS, Bates DM, Chu BB, German CA, Ji SS, Keys KL, Kim J, Ko S, Mosher GD, Papp JC, Sobel EM, Zhai J, Zhou JJ, Lange K. Hum Genet. 2019 Mar 26. doi: 10.1007/s00439-019-02001-z. [Epub ahead of print] PMID: 30915546

Acknowledgments

This project is supported by the National Institutes of Health under NIGMS awards R01GM053275 and R25GM103774 and NHGRI award R01HG006139.