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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8" />
<meta http-equiv="X-UA-Compatible" content="IE=edge" />
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<link
href="https://cdn.jsdelivr.net/npm/bootstrap@5.0.1/dist/css/bootstrap.min.css"
rel="stylesheet"
integrity="sha384-+0n0xVW2eSR5OomGNYDnhzAbDsOXxcvSN1TPprVMTNDbiYZCxYbOOl7+AMvyTG2x"
crossorigin="anonymous"
/>
<link
rel="stylesheet"
href="https://cdn.jsdelivr.net/npm/bootstrap-icons@1.11.3/font/bootstrap-icons.css"
/>
<link
href="https://api.mapbox.com/mapbox-gl-js/v2.1.1/mapbox-gl.css"
rel="stylesheet"
/>
<link rel="stylesheet" href="style.css" />
<script
src="https://cdn.jsdelivr.net/npm/bootstrap@5.0.2/dist/js/bootstrap.bundle.min.js"
integrity="sha384-MrcW6ZMFYlzcLA8Nl+NtUVF0sA7MsXsP1UyJoMp4YLEuNSfAP+JcXn/tWtIaxVXM"
crossorigin="anonymous"
></script>
<title>Anthony Snead</title>
</head>
<body>
<!-- Navbar -->
<nav class="navbar navbar-expand-lg bg-dark navbar-dark py-3 fixed-top">
<div class="container">
<a href="index.html" class="navbar-brand">Anthony Snead</a>
<button
class="navbar-toggler"
type="button"
data-bs-toggle="collapse"
data-bs-target="#navmenu"
>
<span class="navbar-toggler-icon"></span>
</button>
<div class="collapse navbar-collapse" id="navmenu">
<ul class="navbar-nav ms-auto">
<li class="nav-item">
<a href="about.html" class="nav-link">About</a>
</li>
<li class="nav-item">
<a href="research.html" class="nav-link">Research</a>
</li>
<li class="nav-item">
<a href="publications.html" class="nav-link">Publications</a>
</li>
<li class="nav-item">
<a href="outreach.html" class="nav-link">Outreach</a>
</li>
</ul>
</div>
</div>
</nav>
<!-- Showcase / Hero -->
<section class="bg-dark text-light p-2 text-center text-sm-start">
<div class="container">
<div class="d-sm-flex align-items-center justify-content-between">
<div>
<h1>
The Genomics of Biological Responses to
<span class="text-warning">Novelty</span>
</h1>
<h2 class="lead my-4">
"Nothing in Biology Makes Sense Except in the Light of Evolution"
<br />
- Theodosius Dobzhansky
</h2>
<a href="research.html" class="btn btn-primary btn-lg">
Learn About My Research
</a>
</div>
<img
class="img-fluid w-30 mx-4 my-2 d-none d-sm-block"
src="img/Logo.svg"
alt=""
width="350"
height="350"
/>
</div>
</div>
</section>
<!-- Overview -->
<section id="overview" class="py-5">
<div class="container">
<div class="section-header text-center">
<h2 class="section-title">Overview</h2>
<p class="section-subtitle">
My research integrates across disciplines to interrogate the fundamental processes
that drive how biological systems respond to novelty across scales. How organisms
respond to novel conditions is fundamentally shaped by the structure of their genomes,
but the rules governing how genome organization drives these responses remain unclear.
Using a diversity of non-model systems, I investigate how genome architecture dictates
evolutionary responses to novelty — from the molecular mechanisms that generate
phenotypic variation to the evolutionary and ecological processes that shape it across
populations and lineages.
</p>
</div>
</div>
</section>
<!-- Flow + Pillars (between Overview and Collaboration) -->
<section id="research-core" class="py-5 bg-light">
<div class="container">
<!-- Flow / pipeline -->
<div class="flow-wrap p-3 p-md-4 mb-4">
<div class="row g-3 align-items-center text-center">
<div class="col-12 col-md">
<div class="flow-step">
<div class="flow-icon"><i class="bi bi-bounding-box"></i></div>
<div class="flow-label">Genome Architecture</div>
<div class="flow-small">SNPs • Structural Variants • Repeats</div>
</div>
</div>
<div class="col-12 col-md-auto d-none d-md-block">
<div class="flow-arrow"><i class="bi bi-arrow-right"></i></div>
</div>
<div class="col-12 col-md">
<div class="flow-step">
<div class="flow-icon"><i class="bi bi-diagram-2"></i></div>
<div class="flow-label">Molecular Mechanisms</div>
<div class="flow-small">Isoforms • Expression • Chromatin</div>
</div>
</div>
<div class="col-12 col-md-auto d-none d-md-block">
<div class="flow-arrow"><i class="bi bi-arrow-right"></i></div>
</div>
<div class="col-12 col-md">
<div class="flow-step">
<div class="flow-icon"><i class="bi bi-activity"></i></div>
<div class="flow-label">Traits</div>
<div class="flow-small">Physiology • Plasticity • Morphology</div>
</div>
</div>
<div class="col-12 col-md-auto d-none d-md-block">
<div class="flow-arrow"><i class="bi bi-arrow-right"></i></div>
</div>
<div class="col-12 col-md">
<div class="flow-step">
<div class="flow-icon"><i class="bi bi-globe2"></i></div>
<div class="flow-label">Evolutionary Responses</div>
<div class="flow-small">Macro • Micro</div>
</div>
</div>
</div>
</div>
<!-- Pillar cards (no buttons) -->
<div class="row g-4">
<div class="col-md-6 col-lg-3">
<div class="card h-100 shadow-sm feature-card">
<div class="card-body">
<h5 class="card-title">Genome Architecture</h5>
<p class="card-text mb-0">
How genome organization shapes the distribution of variation—and the routes
available to evolution.
</p>
</div>
</div>
</div>
<div class="col-md-6 col-lg-3">
<div class="card h-100 shadow-sm feature-card">
<div class="card-body">
<h5 class="card-title">Pangenomics & Structural Variants</h5>
<p class="card-text mb-0">
Building species-level genomic representations to discover, genotype,
and interpret structural variation.
</p>
</div>
</div>
</div>
<div class="col-md-6 col-lg-3">
<div class="card h-100 shadow-sm feature-card">
<div class="card-body">
<h5 class="card-title">Molecular Mechanisms</h5>
<p class="card-text mb-0">
Connecting variants to isoform-level expression and chromatin state to identify
causal molecular pathways.
</p>
</div>
</div>
</div>
<div class="col-md-6 col-lg-3">
<div class="card h-100 shadow-sm feature-card">
<div class="card-body">
<h5 class="card-title">Cross-Scale Evolution</h5>
<p class="card-text mb-0">
Integrating macroevolutionary shifts in genome architecture with microevolutionary
trait change and plasticity.
</p>
</div>
</div>
</div>
</div>
</div>
</section>
<!-- Collaboration -->
<section id="Collab" class="p-5 bg-dark text-light">
<div class="container">
<div class="row align-items-center justify-content-between">
<div class="col-md p-5">
<h2>
Interested in Collaborating?
<span class="text-warning">Reach out!</span>
</h2>
<p>
I am a firm believer that collaborative science is not only the future but essential
for the forward progression of science. Some of my most interesting research projects
stem from highly interdisciplinary and collaborative teams. If you have a project or
research idea that you think I may be able to help with, reach out! I am always open to
new ideas and applying my skills to new and interesting questions.
</p>
<button
type="button"
class="bi bi-chevron-right btn-primary"
data-bs-toggle="modal"
data-bs-target="#popupModal"
>
Contact Me
</button>
</div>
<div class="col-md">
<img src="img/Collaboration.svg" class="img-fluid" alt="" />
</div>
</div>
</div>
</section>
<!-- Popup Modal -->
<div
class="modal fade"
id="popupModal"
tabindex="-1"
aria-labelledby="popupModalLabel"
aria-hidden="true"
>
<div class="modal-dialog">
<div class="modal-content">
<div class="modal-header">
<h5 class="modal-title" id="popupModalLabel">Contact Me</h5>
<button
type="button"
class="btn-close"
data-bs-dismiss="modal"
aria-label="Close"
></button>
</div>
<div class="modal-body">
<form id="contact_form" name="contact_form" method="post">
<div class="mb-5">
<label for="email_addr">Email address</label>
<input
type="email"
required
maxlength="50"
class="form-control"
id="email_addr"
name="email"
placeholder="name@example.com"
/>
</div>
<div class="mb-5">
<label for="name_input">Name</label>
<input
type="text"
required
maxlength="50"
class="form-control"
id="name_input"
name="name"
placeholder="Name"
/>
</div>
<div class="mb-5">
<label for="subject_input">Subject</label>
<input
type="text"
required
maxlength="50"
class="form-control"
id="subject_input"
name="Subject"
placeholder="Subject"
/>
</div>
<div class="mb-5">
<label for="message">Message</label>
<textarea
class="form-control"
id="message"
name="message"
rows="3"
required
></textarea>
</div>
<button type="submit" class="btn btn-primary">Submit</button>
</form>
</div>
</div>
</div>
</div>
<!-- White Space -->
<section id="learn" class="p-5 bg-light text-light">
<div class="container"></div>
</section>
<!-- Footer -->
<footer class="p-5 bg-dark text-white text-center position-relative">
<div class="container">
<p class="lead">
Made with Bootstrap -
<a
href="https://github.com/anthonysnead/anthonysnead.github.io"
class="link-primary"
target="_blank"
rel="noreferrer"
>See the Code!</a
>
</p>
<a href="#" class="position-absolute bottom-0 end-0 p-5">
<i class="bi bi-arrow-up-circle h1"></i>
</a>
</div>
</footer>
<script
id="ratufa_loader"
src="https://www.ratufa.io/c/ld.js?f=f0viwx6p&n=n1.ratufa.io"
></script>
</body>
</html>