diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/function-url-origin.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/function-url-origin.ts
index 70c9b6a8997f2..b2d48da162667 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/function-url-origin.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/function-url-origin.ts
@@ -12,7 +12,8 @@ import { lit } from '../../core/lib/private/literal-string';
 export interface FunctionUrlOriginProps extends cloudfront.OriginProps {
   /**
    * Specifies how long, in seconds, CloudFront waits for a response from the origin.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the origin response timeout quota, which is
+   * adjustable, so the effective maximum depends on the target account.
    *
    * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
    * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
@@ -23,10 +24,11 @@ export interface FunctionUrlOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront persists its connection to the origin.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the keep-alive timeout per origin quota,
+   * which is adjustable, so the effective maximum depends on the target account.
    *
-   * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
-   * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
+   * The default quota allows up to 300 seconds; higher values require an approved limit increase
+   * in the target account, and otherwise produce an error at deploy time.
    *
    * @default Duration.seconds(5)
    */
@@ -77,8 +79,8 @@ export class FunctionUrlOrigin extends cloudfront.OriginBase {
     const domainName = cdk.Fn.select(2, cdk.Fn.split('/', lambdaFunctionUrl.url));
     super(domainName, props);
 
-    validateSecondsInRangeOrUndefined('readTimeout', 1, 180, props.readTimeout);
-    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, 180, props.keepaliveTimeout);
+    validateSecondsInRangeOrUndefined('readTimeout', 1, undefined, props.readTimeout);
+    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, undefined, props.keepaliveTimeout);
     this.validateResponseCompletionTimeoutWithReadTimeout(props.responseCompletionTimeout, props.readTimeout);
   }
 
@@ -109,8 +111,8 @@ class FunctionUrlOriginWithOAC extends cloudfront.OriginBase {
 
     this.props = props;
 
-    validateSecondsInRangeOrUndefined('readTimeout', 1, 180, props.readTimeout);
-    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, 180, props.keepaliveTimeout);
+    validateSecondsInRangeOrUndefined('readTimeout', 1, undefined, props.readTimeout);
+    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, undefined, props.keepaliveTimeout);
   }
 
   protected renderCustomOriginConfig(): cloudfront.CfnDistribution.CustomOriginConfigProperty | undefined {
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/http-origin.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/http-origin.ts
index d0a42ef5c056f..05ced39c93cc6 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/http-origin.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/http-origin.ts
@@ -38,7 +38,8 @@ export interface HttpOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront waits for a response from the origin, also known as the origin response timeout.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the origin response timeout quota, which is
+   * adjustable, so the effective maximum depends on the target account.
    *
    * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
    * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
@@ -49,10 +50,11 @@ export interface HttpOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront persists its connection to the origin.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the keep-alive timeout per origin quota,
+   * which is adjustable, so the effective maximum depends on the target account.
    *
-   * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
-   * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
+   * The default quota allows up to 300 seconds; higher values require an approved limit increase
+   * in the target account, and otherwise produce an error at deploy time.
    *
    * @default Duration.seconds(5)
    */
@@ -75,8 +77,8 @@ export class HttpOrigin extends cloudfront.OriginBase {
   constructor(domainName: string, private readonly props: HttpOriginProps = {}) {
     super(domainName, props);
 
-    validateSecondsInRangeOrUndefined('readTimeout', 1, 180, props.readTimeout);
-    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, 180, props.keepaliveTimeout);
+    validateSecondsInRangeOrUndefined('readTimeout', 1, undefined, props.readTimeout);
+    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, undefined, props.keepaliveTimeout);
     this.validateResponseCompletionTimeoutWithReadTimeout(props.responseCompletionTimeout, props.readTimeout);
 
     this.validatePortNumber('httpPort', props.httpPort);
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/private/utils.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/private/utils.ts
index edf4aaa85fac1..18031472d9e99 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/private/utils.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/private/utils.ts
@@ -3,11 +3,16 @@ import { lit } from '../../../core/lib/private/literal-string';
 
 /**
  * Throws an error if a duration is defined and not an integer number of seconds within a range.
+ *
+ * Pass `undefined` for `max` to validate the lower bound only. This is for values whose upper
+ * bound is an adjustable service quota, so the effective maximum depends on the target account
+ * and can only be enforced by the service at deploy time.
  */
-export function validateSecondsInRangeOrUndefined(name: string, min: number, max: number, duration?: cdk.Duration) {
+export function validateSecondsInRangeOrUndefined(name: string, min: number, max: number | undefined, duration?: cdk.Duration) {
   if (duration === undefined) { return; }
   const value = duration.toSeconds();
-  if (!Number.isInteger(value) || value < min || value > max) {
-    throw new cdk.UnscopedValidationError(lit`InvalidDurationRange`, `${name}: Must be an int between ${min} and ${max} seconds (inclusive); received ${value}.`);
+  if (!Number.isInteger(value) || value < min || (max !== undefined && value > max)) {
+    const range = max !== undefined ? `between ${min} and ${max} seconds (inclusive)` : `${min} seconds or greater`;
+    throw new cdk.UnscopedValidationError(lit`InvalidDurationRange`, `${name}: Must be an int ${range}; received ${value}.`);
   }
 }
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/rest-api-origin.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/rest-api-origin.ts
index 03518a532d685..a5160f621841c 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/rest-api-origin.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/rest-api-origin.ts
@@ -9,7 +9,8 @@ import * as cdk from '../../core';
 export interface RestApiOriginProps extends cloudfront.OriginProps {
   /**
    * Specifies how long, in seconds, CloudFront waits for a response from the origin, also known as the origin response timeout.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the origin response timeout quota, which is
+   * adjustable, so the effective maximum depends on the target account.
    *
    * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
    * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
@@ -20,10 +21,11 @@ export interface RestApiOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront persists its connection to the origin.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the keep-alive timeout per origin quota,
+   * which is adjustable, so the effective maximum depends on the target account.
    *
-   * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
-   * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
+   * The default quota allows up to 300 seconds; higher values require an approved limit increase
+   * in the target account, and otherwise produce an error at deploy time.
    *
    * @default Duration.seconds(5)
    */
@@ -43,8 +45,8 @@ export class RestApiOrigin extends cloudfront.OriginBase {
       ...props,
     });
 
-    validateSecondsInRangeOrUndefined('readTimeout', 1, 180, props.readTimeout);
-    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, 180, props.keepaliveTimeout);
+    validateSecondsInRangeOrUndefined('readTimeout', 1, undefined, props.readTimeout);
+    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, undefined, props.keepaliveTimeout);
     this.validateResponseCompletionTimeoutWithReadTimeout(props.responseCompletionTimeout, props.readTimeout);
   }
 
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/vpc-origin.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/vpc-origin.ts
index 55acf4fd40773..a6b501dc38b2f 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/lib/vpc-origin.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/lib/vpc-origin.ts
@@ -18,7 +18,8 @@ export interface VpcOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront waits for a response from the origin, also known as the origin response timeout.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the origin response timeout quota, which is
+   * adjustable, so the effective maximum depends on the target account.
    *
    * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
    * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
@@ -29,10 +30,11 @@ export interface VpcOriginProps extends cloudfront.OriginProps {
 
   /**
    * Specifies how long, in seconds, CloudFront persists its connection to the origin.
-   * The valid range is from 1 to 180 seconds, inclusive.
+   * The minimum is 1 second. The maximum is governed by the keep-alive timeout per origin quota,
+   * which is adjustable, so the effective maximum depends on the target account.
    *
-   * Note that values over 60 seconds are possible only after a limit increase request for the origin response timeout quota
-   * has been approved in the target account; otherwise, values over 60 seconds will produce an error at deploy time.
+   * The default quota allows up to 300 seconds; higher values require an approved limit increase
+   * in the target account, and otherwise produce an error at deploy time.
    *
    * @default Duration.seconds(5)
    */
@@ -83,8 +85,8 @@ export abstract class VpcOrigin extends cloudfront.OriginBase {
   protected constructor(domainName: string, protected readonly props: VpcOriginProps) {
     super(domainName, props);
 
-    validateSecondsInRangeOrUndefined('readTimeout', 1, 180, props.readTimeout);
-    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, 180, props.keepaliveTimeout);
+    validateSecondsInRangeOrUndefined('readTimeout', 1, undefined, props.readTimeout);
+    validateSecondsInRangeOrUndefined('keepaliveTimeout', 1, undefined, props.keepaliveTimeout);
   }
 
   protected renderVpcOriginConfig(): cloudfront.CfnDistribution.VpcOriginConfigProperty | undefined {
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/test/http-origin.test.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/test/http-origin.test.ts
index 373835feec0d7..7bf0cb12953bc 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/test/http-origin.test.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/test/http-origin.test.ts
@@ -71,20 +71,29 @@ test('renders an example with all available props', () => {
 
 test.each([
   Duration.seconds(0),
+])('validates readTimeout is at least 1 second', (readTimeout) => {
+  expect(() => {
+    new HttpOrigin('www.example.com', {
+      readTimeout,
+    });
+  }).toThrow(`readTimeout: Must be an int 1 seconds or greater; received ${readTimeout.toSeconds()}.`);
+});
+
+test.each([
   Duration.seconds(181),
   Duration.minutes(5),
-])('validates readTimeout is an integer between 1 and 180 seconds - out of bounds', (readTimeout) => {
+])('allows readTimeout above the default quota, which the service validates at deploy time', (readTimeout) => {
   expect(() => {
     new HttpOrigin('www.example.com', {
       readTimeout,
     });
-  }).toThrow(`readTimeout: Must be an int between 1 and 180 seconds (inclusive); received ${readTimeout.toSeconds()}.`);
+  }).not.toThrow();
 });
 
 test.each([
   Duration.seconds(0.5),
   Duration.seconds(60.5),
-])('validates readTimeout is an integer between 1 and 180 seconds - not an int', (readTimeout) => {
+])('validates readTimeout is a whole number of seconds', (readTimeout) => {
   expect(() => {
     new HttpOrigin('www.example.com', {
       readTimeout,
@@ -94,20 +103,29 @@ test.each([
 
 test.each([
   Duration.seconds(0),
+])('validates keepaliveTimeout is at least 1 second', (keepaliveTimeout) => {
+  expect(() => {
+    new HttpOrigin('www.example.com', {
+      keepaliveTimeout,
+    });
+  }).toThrow(`keepaliveTimeout: Must be an int 1 seconds or greater; received ${keepaliveTimeout.toSeconds()}.`);
+});
+
+test.each([
   Duration.seconds(181),
   Duration.minutes(5),
-])('validates keepaliveTimeout is an integer between 1 and 180 seconds - out of bounds', (keepaliveTimeout) => {
+])('allows keepaliveTimeout within the default quota, which the service validates at deploy time', (keepaliveTimeout) => {
   expect(() => {
     new HttpOrigin('www.example.com', {
       keepaliveTimeout,
     });
-  }).toThrow(`keepaliveTimeout: Must be an int between 1 and 180 seconds (inclusive); received ${keepaliveTimeout.toSeconds()}.`);
+  }).not.toThrow();
 });
 
 test.each([
   Duration.seconds(0.5),
   Duration.seconds(60.5),
-])('validates keepaliveTimeout is an integer between 1 and 180 seconds - not an int', (keepaliveTimeout) => {
+])('validates keepaliveTimeout is a whole number of seconds', (keepaliveTimeout) => {
   expect(() => {
     new HttpOrigin('www.example.com', {
       keepaliveTimeout,
diff --git a/packages/aws-cdk-lib/aws-cloudfront-origins/test/vpc-origin.test.ts b/packages/aws-cdk-lib/aws-cloudfront-origins/test/vpc-origin.test.ts
index a62d18bb6ac81..be43f0042295a 100644
--- a/packages/aws-cdk-lib/aws-cloudfront-origins/test/vpc-origin.test.ts
+++ b/packages/aws-cdk-lib/aws-cloudfront-origins/test/vpc-origin.test.ts
@@ -206,9 +206,21 @@ test('VPC origin from an imported VpcOrigin resource', () => {
 
 test.each([
   Duration.seconds(0),
+])('VPC origin throws when readTimeout is %s - below the minimum', (readTimeout) => {
+  // GIVEN
+  const vpc = new ec2.Vpc(stack, 'Vpc');
+  const loadBalancer = new elbv2.ApplicationLoadBalancer(stack, 'ALB', { vpc });
+
+  // WHEN
+  expect(() => {
+    VpcOrigin.withApplicationLoadBalancer(loadBalancer, { readTimeout });
+  }).toThrow(`readTimeout: Must be an int 1 seconds or greater; received ${readTimeout.toSeconds()}`);
+});
+
+test.each([
   Duration.seconds(181),
   Duration.minutes(5),
-])('VPC origin throws when readTimeout is %s - out of bounds', (readTimeout) => {
+])('VPC origin allows readTimeout of %s above the default quota', (readTimeout) => {
   // GIVEN
   const vpc = new ec2.Vpc(stack, 'Vpc');
   const loadBalancer = new elbv2.ApplicationLoadBalancer(stack, 'ALB', { vpc });
@@ -216,14 +228,26 @@ test.each([
   // WHEN
   expect(() => {
     VpcOrigin.withApplicationLoadBalancer(loadBalancer, { readTimeout });
-  }).toThrow(`readTimeout: Must be an int between 1 and 180 seconds (inclusive); received ${readTimeout.toSeconds()}`);
+  }).not.toThrow();
 });
 
 test.each([
   Duration.seconds(0),
+])('VPC origin throws when keepaliveTimeout is %s - below the minimum', (keepaliveTimeout) => {
+  // GIVEN
+  const vpc = new ec2.Vpc(stack, 'Vpc');
+  const loadBalancer = new elbv2.ApplicationLoadBalancer(stack, 'ALB', { vpc });
+
+  // WHEN
+  expect(() => {
+    VpcOrigin.withApplicationLoadBalancer(loadBalancer, { keepaliveTimeout });
+  }).toThrow(`keepaliveTimeout: Must be an int 1 seconds or greater; received ${keepaliveTimeout.toSeconds()}`);
+});
+
+test.each([
   Duration.seconds(181),
   Duration.minutes(5),
-])('VPC origin throws when keepaliveTimeout is %s - out of bounds', (keepaliveTimeout) => {
+])('VPC origin allows keepaliveTimeout of %s within the default quota', (keepaliveTimeout) => {
   // GIVEN
   const vpc = new ec2.Vpc(stack, 'Vpc');
   const loadBalancer = new elbv2.ApplicationLoadBalancer(stack, 'ALB', { vpc });
@@ -231,7 +255,7 @@ test.each([
   // WHEN
   expect(() => {
     VpcOrigin.withApplicationLoadBalancer(loadBalancer, { keepaliveTimeout });
-  }).toThrow(`keepaliveTimeout: Must be an int between 1 and 180 seconds (inclusive); received ${keepaliveTimeout.toSeconds()}`);
+  }).not.toThrow();
 });
 
 test('VPC origin throws when no domainName is specified', () => {