diff --git a/py/setup.py b/py/setup.py
index 0f2c42a1..63bfc423 100644
--- a/py/setup.py
+++ b/py/setup.py
@@ -29,6 +29,8 @@
     "doc": ["pydoc-markdown"],
     "openai-agents": ["openai-agents"],
     "otel": ["opentelemetry-api", "opentelemetry-sdk", "opentelemetry-exporter-otlp-proto-http"],
+    # orjson is not compatible with PyPy, so we exclude it for that platform
+    "performance": ["orjson; platform_python_implementation != 'PyPy'"],
     "temporal": ["temporalio>=1.19.0; python_version>='3.10'"],
 }