UI becomes less responsive to left clicking the mouse and dragging through the colonist list. As a result, some colonists are skipped, or the selection doesn't initiate due to left click not being registered.
The conditions are not fully clear, yet I confirmed it's related to this mod (possibly race mods make it worse). If this happens, it's going to be worse with the number of colonists. It's not required though, as I had one game with a handful of colonists and big lags regardless. However, I can't reproduce it with a new game where I just make a bunch of wanderers join.
Here's the log from one of the games, where I did tests specifically with this mod and without it https://pastebin.com/Wgr0Qat7. That game wasn't started with it. I also validated that removal of practically all other mods (besides Harmony etc.) doesn't change it. Here's the save file Mecha Explorers (Permadeath).zip.
Here's the log from another game, where I haven't done extensive tests, but where it lags even with handful of colonists https://pastebin.com/jRFBCKSq. Here's the save file
Lava Explorers (Permadeath).zip.