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code for the figures of the manuscript<!-- --> <a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002861">Romani et al. (2024)</a>.<br/><a href="https://dataverse.harvard.edu/dataset.xhtml?persistentId=doi:10.7910/DVN/UGOQWE">github.com/BlueBrain/rat_ca1_model_code/</a></p><h2>Simulating a Hippocampus Microcircuit</h2><p>A massive open online course (MOOC) about the CA1 microcircuit.<br/><a href="https://www.edx.org/learn/neuroscience/ecole-polytechnique-federale-de-lausanne-simulating-a-hippocampus-microcircuit">edx.org/learn/neuroscience/ecole-polytechnique-federale-de-lausanne-simulating-a-hippocampus-microcircuit</a></p><h2>Publications</h2><ul><li>Romani et al. Community-based Reconstruction and Simulation of a Full-scale Model of Region CA1 of Rat Hippocampus. BioRxiv.<br/><a href="https://www.biorxiv.org/content/10.1101/2023.05.17.541167v2">https://www.biorxiv.org/content/10.1101/2023.05.17.541167v2</a></li><li>Bologna L.L., Tocco A., Smiriglia R., Romani A., Schürmann F., Migliore M. (2023). Online interoperable resources for building hippocampal neuron models via the Hippocampus Hub. Front Neuroinform. 2023 Nov 1:17:1271059. doi: 10.3389/fninf.2023.1271059. eCollection 2023.</li><li>Romani A., Schürmann F., Markram H., and Migliore M. (2022). Reconstruction of the Hippocampus. Adv. Exp. Med. Biol. 1359, 261–283. 10.1007/978-3-030-89439-9_11.</li><li>Sáray S., Rössert C.A., Appukuttan S., Migliore R., Vitale P., Lupascu C.A., Bologna L.L., Van Geit W., Romani A., Davison A.P., et al. (2021). HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data. PLoS Comput. Biol. 17, e1008114. 10.1371/journal.pcbi.1008114.</li><li>Ecker A., Romani A., Sáray S., Káli S., Migliore M., Falck J., Lange S., Mercer A., Thomson A.M., Muller E., Reimann M.W., Ramaswamy, S. (2020). Data-driven integration of hippocampal CA1 synaptic physiology in silico. Hippocampus. 2020 Nov;30(11):1129-1145. doi: 10.1002/hipo.23220. Epub 2020 Jun 10.<!-- --> </li><li>Migliore R., Lupascu C.A., Bologna L.L., Romani A., Courcol J.-D., Antonel S., Van Geit W.A.H., Thomson A.M., Mercer A., Lange S., et al. (2018). The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow. PLoS Comput. Biol. 14, e1006423. 10.1371/journal.pcbi.1006423.<!-- --> </li></ul></div></div><footer class="styles_footer__Xr_4w py-12 relative"><div class="w-full max-w-screen-xl mx-auto xl:px-0 xs:px-8"><h2 class="text-white text-xl">The Hippocampus Hub Explorer</h2><div class="flex flex-wrap justify-between mt-4"><div class="w-full sm:w-1/3 pr-12 mb-4 xs:mb-12"><a href="https://www.epfl.ch/research/domains/bluebrain/">Blue Brain Project</a><br/><br/><p class="text-gray-400">EPFL/Campus Biotech <br/>Chemin des Mines 9 <br/>CH-1202 Geneva <br/>Switzerland <br/></p></div><div class="w-full sm:w-1/3 pr-12 mb-4 xs:mb-12"><ul class="list-none p-0"><li class="mb-2"><a class="text-white hover:underline" href="/model/terms-of-use">Terms of Use</a></li><li class="mb-2"><a class="text-white hover:underline" href="/model/privacy-policy">Privacy Policy</a></li><li class="mb-2"><a class="text-white hover:underline" href="/model/cookies-policy">Cookies Policy</a></li></ul></div><div class="w-full sm:w-1/3 pr-12 mb-4 xs:mb-12"><ul class="list-none p-0"><li class="mb-1"><a class="text-white hover:underline" href="/model">Home</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model">Explore Models</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model/build">Build Models</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model#resources">Resources</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model#terms">Terms & Conditions</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model/resources">Resources</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model/glossary">Glossary</a></li><li class="mb-1"><a class="text-white hover:underline" href="/model#contact">Contact Us</a></li></ul><div class="mt-4"><p class="text-white">Follow the Blue Brain</p><div class="flex space-x-2 mt-2"><a href="https://x.com/bluebrainpjt?lang=en"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 448 512" height="1.5rem" width="1.5rem" xmlns="http://www.w3.org/2000/svg"><path d="M400 32H48C21.5 32 0 53.5 0 80v352c0 26.5 21.5 48 48 48h352c26.5 0 48-21.5 48-48V80c0-26.5-21.5-48-48-48zm-48.9 158.8c.2 2.8.2 5.7.2 8.5 0 86.7-66 186.6-186.6 186.6-37.2 0-71.7-10.8-100.7-29.4 5.3.6 10.4.8 15.8.8 30.7 0 58.9-10.4 81.4-28-28.8-.6-53-19.5-61.3-45.5 10.1 1.5 19.2 1.5 29.6-1.2-30-6.1-52.5-32.5-52.5-64.4v-.8c8.7 4.9 18.9 7.9 29.6 8.3a65.447 65.447 0 0 1-29.2-54.6c0-12.2 3.2-23.4 8.9-33.1 32.3 39.8 80.8 65.8 135.2 68.6-9.3-44.5 24-80.6 64-80.6 18.9 0 35.9 7.9 47.9 20.7 14.8-2.8 29-8.3 41.6-15.8-4.9 15.2-15.2 28-28.8 36.1 13.2-1.4 26-5.1 37.8-10.2-8.9 13.1-20.1 24.7-32.9 34z"></path></svg></a><a href="https://www.linkedin.com/showcase/blue-brain-project/"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 448 512" height="1.5em" width="1.5em" xmlns="http://www.w3.org/2000/svg"><path d="M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z"></path></svg></a><a href="https://www.youtube.com/user/Bluebrainpjt/featured/"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 448 512" height="1.5em" width="1.5em" xmlns="http://www.w3.org/2000/svg"><path d="M186.8 202.1l95.2 54.1-95.2 54.1V202.1zM448 80v352c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V80c0-26.5 21.5-48 48-48h352c26.5 0 48 21.5 48 48zm-42 176.3s0-59.6-7.6-88.2c-4.2-15.8-16.5-28.2-32.2-32.4C337.9 128 224 128 224 128s-113.9 0-142.2 7.7c-15.7 4.2-28 16.6-32.2 32.4-7.6 28.5-7.6 88.2-7.6 88.2s0 59.6 7.6 88.2c4.2 15.8 16.5 27.7 32.2 31.9C110.1 384 224 384 224 384s113.9 0 142.2-7.7c15.7-4.2 28-16.1 32.2-31.9 7.6-28.5 7.6-88.1 7.6-88.1z"></path></svg></a></div></div></div></div><div class="flex justify-between mt-3"><div class="w-full text-gray-400"><p>© EPFL | Blue Brain Project | 2005-2024</p></div></div></div></footer></div><script id="__NEXT_DATA__" type="application/json" crossorigin="">{"props":{"pageProps":{}},"page":"/resources","query":{},"buildId":"mvamN77UK2b3x3FVna4aC","assetPrefix":"/model","nextExport":true,"autoExport":true,"isFallback":false,"scriptLoader":[]}</script></body></html>