diff --git a/docs/pages/material-ui/api/autocomplete.json b/docs/pages/material-ui/api/autocomplete.json
index 5e12636af35030..d0922e78f8ff63 100644
--- a/docs/pages/material-ui/api/autocomplete.json
+++ b/docs/pages/material-ui/api/autocomplete.json
@@ -161,14 +161,14 @@
     "slotProps": {
       "type": {
         "name": "shape",
-        "description": "{ chip?: func<br>&#124;&nbsp;object, clearIndicator?: func<br>&#124;&nbsp;object, listbox?: func<br>&#124;&nbsp;object, paper?: func<br>&#124;&nbsp;object, popper?: func<br>&#124;&nbsp;object, popupIndicator?: func<br>&#124;&nbsp;object, root?: func<br>&#124;&nbsp;object }"
+        "description": "{ chip?: func<br>&#124;&nbsp;object, clearIndicator?: func<br>&#124;&nbsp;object, listbox?: func<br>&#124;&nbsp;object, noOptionsContainer?: func<br>&#124;&nbsp;object, paper?: func<br>&#124;&nbsp;object, popper?: func<br>&#124;&nbsp;object, popupIndicator?: func<br>&#124;&nbsp;object, root?: func<br>&#124;&nbsp;object }"
       },
       "default": "{}"
     },
     "slots": {
       "type": {
         "name": "shape",
-        "description": "{ clearIndicator?: elementType, listbox?: elementType, paper?: elementType, popper?: elementType, popupIndicator?: elementType, root?: elementType }"
+        "description": "{ clearIndicator?: elementType, listbox?: elementType, noOptionsContainer?: elementType, paper?: elementType, popper?: elementType, popupIndicator?: elementType, root?: elementType }"
       },
       "default": "{}"
     },
@@ -211,6 +211,12 @@
       "default": "'ul'",
       "class": "MuiAutocomplete-listbox"
     },
+    {
+      "name": "noOptionsContainer",
+      "description": "The component used to render the \"no options\" container.",
+      "default": "'div'",
+      "class": "MuiAutocomplete-noOptionsContainer"
+    },
     {
       "name": "paper",
       "description": "The component used to render the body of the popup.",
diff --git a/docs/translations/api-docs/autocomplete/autocomplete.json b/docs/translations/api-docs/autocomplete/autocomplete.json
index 7eb570fb34d844..46016b6f5ac057 100644
--- a/docs/translations/api-docs/autocomplete/autocomplete.json
+++ b/docs/translations/api-docs/autocomplete/autocomplete.json
@@ -319,6 +319,7 @@
   "slotDescriptions": {
     "clearIndicator": "The component used to render the clear indicator element.",
     "listbox": "The component used to render the listbox.",
+    "noOptionsContainer": "The component used to render the &quot;no options&quot; container.",
     "paper": "The component used to render the body of the popup.",
     "popper": "The component used to position the popup.",
     "popupIndicator": "The component used to render the popup indicator element.",
diff --git a/packages/mui-material/src/Autocomplete/Autocomplete.d.ts b/packages/mui-material/src/Autocomplete/Autocomplete.d.ts
index bbd514a792a6d0..4bddc19567a1fe 100644
--- a/packages/mui-material/src/Autocomplete/Autocomplete.d.ts
+++ b/packages/mui-material/src/Autocomplete/Autocomplete.d.ts
@@ -23,6 +23,7 @@ import { CreateSlotsAndSlotProps, SlotProps } from '../utils/types';
 
 export interface AutocompletePaperSlotPropsOverrides {}
 export interface AutocompletePopperSlotPropsOverrides {}
+export interface AutocompleteNoOptionsContainerSlotPropsOverrides {}
 
 export {
   AutocompleteChangeDetails,
@@ -136,6 +137,11 @@ export interface AutocompleteSlots {
    * @default 'ul'
    */
   listbox: React.JSXElementConstructor<React.HTMLAttributes<HTMLElement>>;
+  /**
+   * The component used to render the "no options" container.
+   * @default 'div'
+   */
+  noOptionsContainer: React.ElementType;
   /**
    * The component used to render the body of the popup.
    * @default Paper
@@ -185,6 +191,11 @@ export type AutocompleteSlotsAndSlotProps<
       {},
       AutocompleteOwnerState<Value, Multiple, DisableClearable, FreeSolo, ChipComponent>
     >;
+    noOptionsContainer: SlotProps<
+      'div',
+      AutocompleteNoOptionsContainerSlotPropsOverrides,
+      AutocompleteOwnerState<Value, Multiple, DisableClearable, FreeSolo, ChipComponent>
+    >;
     paper: SlotProps<
       React.ElementType<Partial<PaperProps>>,
       AutocompletePaperSlotPropsOverrides,
diff --git a/packages/mui-material/src/Autocomplete/Autocomplete.js b/packages/mui-material/src/Autocomplete/Autocomplete.js
index 8470ab477a273c..c3135e29314a98 100644
--- a/packages/mui-material/src/Autocomplete/Autocomplete.js
+++ b/packages/mui-material/src/Autocomplete/Autocomplete.js
@@ -59,6 +59,7 @@ const useUtilityClasses = (ownerState) => {
     listbox: ['listbox'],
     loading: ['loading'],
     noOptions: ['noOptions'],
+    noOptionsContainer: ['noOptionsContainer'],
     option: ['option'],
     groupLabel: ['groupLabel'],
     groupUl: ['groupUl'],
@@ -604,6 +605,18 @@ const Autocomplete = React.forwardRef(function Autocomplete(inProps, ref) {
     className: classes.paper,
   });
 
+  const [NoOptionsSlot, noOptionsProps] = useSlot('noOptionsContainer', {
+    elementType: 'div',
+    externalForwardedProps,
+    ownerState,
+    className: classes.noOptionsContainer,
+    additionalProps: {
+      role: 'status',
+      'aria-live': 'polite',
+      'aria-atomic': 'true',
+    },
+  });
+
   const [PopperSlot, popperProps] = useSlot('popper', {
     elementType: Popper,
     externalForwardedProps,
@@ -796,19 +809,20 @@ const Autocomplete = React.forwardRef(function Autocomplete(inProps, ref) {
                 {loadingText}
               </AutocompleteLoading>
             ) : null}
-            {renderedOptions.length === 0 && !freeSolo && !loading ? (
-              <AutocompleteNoOptions
-                className={classes.noOptions}
-                ownerState={ownerState}
-                role="presentation"
-                onMouseDown={(event) => {
-                  // Prevent input blur when interacting with the "no options" content
-                  event.preventDefault();
-                }}
-              >
-                {noOptionsText}
-              </AutocompleteNoOptions>
-            ) : null}
+            <NoOptionsSlot {...noOptionsProps}>
+              {renderedOptions.length === 0 && !freeSolo && !loading ? (
+                <AutocompleteNoOptions
+                  className={classes.noOptions}
+                  ownerState={ownerState}
+                  onMouseDown={(event) => {
+                    // Prevent input blur when interacting with the "no options" content
+                    event.preventDefault();
+                  }}
+                >
+                  {noOptionsText}
+                </AutocompleteNoOptions>
+              ) : null}
+            </NoOptionsSlot>
             {renderedOptions.length > 0 ? (
               <ListboxSlot {...listboxProps}>
                 {renderedOptions.map((option, index) => {
@@ -1232,6 +1246,7 @@ Autocomplete.propTypes /* remove-proptypes */ = {
     chip: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
     clearIndicator: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
     listbox: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
+    noOptionsContainer: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
     paper: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
     popper: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
     popupIndicator: PropTypes.oneOfType([PropTypes.func, PropTypes.object]),
@@ -1244,6 +1259,7 @@ Autocomplete.propTypes /* remove-proptypes */ = {
   slots: PropTypes.shape({
     clearIndicator: PropTypes.elementType,
     listbox: PropTypes.elementType,
+    noOptionsContainer: PropTypes.elementType,
     paper: PropTypes.elementType,
     popper: PropTypes.elementType,
     popupIndicator: PropTypes.elementType,
diff --git a/packages/mui-material/src/Autocomplete/Autocomplete.spec.tsx b/packages/mui-material/src/Autocomplete/Autocomplete.spec.tsx
index cf9baa121a2e52..cd037cc40d891e 100644
--- a/packages/mui-material/src/Autocomplete/Autocomplete.spec.tsx
+++ b/packages/mui-material/src/Autocomplete/Autocomplete.spec.tsx
@@ -151,6 +151,7 @@ function AutocompleteComponentsProps() {
       renderInput={(params) => <TextField {...params} />}
       slotProps={{
         clearIndicator: { size: 'large' },
+        noOptionsContainer: { 'aria-label': 'no results' },
         paper: { elevation: 2 },
         popper: { placement: 'bottom-end' },
         popupIndicator: { size: 'large' },
@@ -170,6 +171,18 @@ function CustomListboxRef() {
   );
 }
 
+function CustomNoOptionsSlot() {
+  const ref = React.useRef<HTMLDivElement>(null);
+  return (
+    <Autocomplete
+      renderInput={(params) => <TextField {...params} />}
+      options={['one', 'two', 'three']}
+      slots={{ noOptionsContainer: 'div' }}
+      slotProps={{ noOptionsContainer: { ref } }}
+    />
+  );
+}
+
 // Tests presence of defaultMuiPrevented in event
 <Autocomplete
   renderInput={(params) => <TextField {...params} />}
diff --git a/packages/mui-material/src/Autocomplete/Autocomplete.test.js b/packages/mui-material/src/Autocomplete/Autocomplete.test.js
index c64005ad1c64da..79788d5feecfbb 100644
--- a/packages/mui-material/src/Autocomplete/Autocomplete.test.js
+++ b/packages/mui-material/src/Autocomplete/Autocomplete.test.js
@@ -93,6 +93,7 @@ describe('<Autocomplete />', () => {
       slots: {
         clearIndicator: { expectedClassName: classes.clearIndicator },
         popupIndicator: { expectedClassName: classes.popupIndicator },
+        noOptionsContainer: { expectedClassName: classes.noOptionsContainer },
       },
       only: [
         'slotsProp',
@@ -4970,6 +4971,78 @@ describe('<Autocomplete />', () => {
     expect(screen.getByTestId('label')).to.have.attribute('data-shrink', 'false');
   });
 
+  describe('prop: noOptionsText', () => {
+    it('should render the no options text when there are no options', () => {
+      render(
+        <Autocomplete
+          open
+          options={[]}
+          renderInput={(params) => <TextField {...params} autoFocus />}
+        />,
+      );
+
+      expect(screen.getByText('No options')).not.to.equal(null);
+    });
+
+    it('should render the custom no options text when there are no options', () => {
+      render(
+        <Autocomplete
+          open
+          options={[]}
+          noOptionsText="No results"
+          renderInput={(params) => <TextField {...params} autoFocus />}
+        />,
+      );
+
+      expect(screen.getByText('No results')).not.to.equal(null);
+    });
+
+    it('should not render the no options text when loading and there are no options', () => {
+      render(
+        <Autocomplete
+          open
+          options={[]}
+          loading
+          renderInput={(params) => <TextField {...params} autoFocus />}
+        />,
+      );
+
+      expect(screen.queryByText('No options')).to.equal(null);
+    });
+
+    it('should not render the no options text when freeSolo is true and there are no options', () => {
+      render(
+        <Autocomplete
+          open
+          options={[]}
+          freeSolo
+          renderInput={(params) => <TextField {...params} autoFocus />}
+        />,
+      );
+
+      expect(screen.queryByText('No options')).to.equal(null);
+    });
+
+    it('should always render a status message container for no options', async () => {
+      const { user } = render(
+        <Autocomplete
+          open
+          options={['one', 'two']}
+          renderInput={(params) => <TextField {...params} autoFocus />}
+        />,
+      );
+
+      const status = screen.getByRole('status');
+      expect(status).to.have.attribute('aria-live', 'polite');
+      expect(status).to.have.attribute('aria-atomic', 'true');
+      expect(status.children).to.have.length(0);
+
+      await user.type(screen.getByRole('combobox'), 'three');
+
+      expect(status.children).to.have.length(1);
+    });
+  });
+
   // https://github.com/mui/material-ui/issues/47203
   it.skipIf(isJsdom())(
     'should not scroll the listbox to the top when listbox is scrolled down and one of the end option is clicked',
diff --git a/packages/mui-material/src/Autocomplete/autocompleteClasses.ts b/packages/mui-material/src/Autocomplete/autocompleteClasses.ts
index 863a1719e46490..2910da37a3164c 100644
--- a/packages/mui-material/src/Autocomplete/autocompleteClasses.ts
+++ b/packages/mui-material/src/Autocomplete/autocompleteClasses.ts
@@ -48,6 +48,8 @@ export interface AutocompleteClasses {
   loading: string;
   /** Styles applied to the no option wrapper. */
   noOptions: string;
+  /** Styles applied to the no option container. */
+  noOptionsContainer: string;
   /** Styles applied to the option elements. */
   option: string;
   /** Styles applied to the group's label elements. */
@@ -86,6 +88,7 @@ const autocompleteClasses: AutocompleteClasses = generateUtilityClasses('MuiAuto
   'listbox',
   'loading',
   'noOptions',
+  'noOptionsContainer',
   'option',
   'groupLabel',
   'groupUl',