diff --git a/Lib/test/test_socket.py b/Lib/test/test_socket.py
index 934b7137096bc0..36fb5829b868b2 100644
--- a/Lib/test/test_socket.py
+++ b/Lib/test/test_socket.py
@@ -7491,6 +7491,67 @@ def detach():
             pass
 
 
+class ReentrantMutationTests(unittest.TestCase):
+    """Regression tests for re-entrant mutation vulnerabilities in sendmsg/recvmsg_into.
+
+    These tests verify that mutating sequences during argument parsing
+    via __buffer__ protocol does not cause crashes.
+
+    See: https://github.com/python/cpython/issues/143988
+    """
+
+    @unittest.skipUnless(hasattr(socket.socket, "sendmsg"),
+                         "sendmsg not supported")
+    def test_sendmsg_reentrant_data_mutation(self):
+        # Test that sendmsg() handles re-entrant mutation of data buffers
+        # via __buffer__ protocol.
+        # See: https://github.com/python/cpython/issues/143988
+        seq = []
+
+        class MutBuffer:
+            def __init__(self):
+                self.tripped = False
+
+            def __buffer__(self, flags):
+                if not self.tripped:
+                    self.tripped = True
+                    seq.clear()
+                return memoryview(b'Hello')
+
+        seq = [MutBuffer(), b'World', b'Test']
+
+        left, right = socket.socketpair()
+        self.addCleanup(left.close)
+        self.addCleanup(right.close)
+        left.sendmsg(seq)
+
+    @unittest.skipUnless(hasattr(socket.socket, "recvmsg_into"),
+                         "recvmsg_into not supported")
+    def test_recvmsg_into_reentrant_buffer_mutation(self):
+        # Test that recvmsg_into() handles re-entrant mutation of buffers
+        # via __buffer__ protocol.
+        # See: https://github.com/python/cpython/issues/143988
+        seq = []
+
+        class MutBuffer:
+            def __init__(self):
+                self.tripped = False
+
+            def __buffer__(self, flags):
+                if not self.tripped:
+                    self.tripped = True
+                    seq.clear()
+                return memoryview(bytearray(100))
+
+        seq = [MutBuffer(), bytearray(100), bytearray(100)]
+
+        left, right = socket.socketpair()
+        self.addCleanup(left.close)
+        self.addCleanup(right.close)
+        left.send(b'Hello World!')
+        right.recvmsg_into(seq)
+
+
 def setUpModule():
     thread_info = threading_helper.threading_setup()
     unittest.addModuleCleanup(threading_helper.threading_cleanup, *thread_info)
diff --git a/Misc/NEWS.d/next/Security/2026-01-18-06-42-47.gh-issue-143988.MtLtCP.rst b/Misc/NEWS.d/next/Security/2026-01-18-06-42-47.gh-issue-143988.MtLtCP.rst
new file mode 100644
index 00000000000000..fcc0cb54934b90
--- /dev/null
+++ b/Misc/NEWS.d/next/Security/2026-01-18-06-42-47.gh-issue-143988.MtLtCP.rst
@@ -0,0 +1,2 @@
+Fixed crashes in :meth:`socket.socket.sendmsg` and :meth:`socket.socket.recvmsg_into`
+that could occur if buffer sequences are concurrently mutated.
diff --git a/Modules/socketmodule.c b/Modules/socketmodule.c
index ee78ad01598262..ad3bdff1e0e9e5 100644
--- a/Modules/socketmodule.c
+++ b/Modules/socketmodule.c
@@ -4527,11 +4527,13 @@ sock_recvmsg_into(PyObject *self, PyObject *args)
                           &buffers_arg, &ancbufsize, &flags))
         return NULL;
 
-    if ((fast = PySequence_Fast(buffers_arg,
-                                "recvmsg_into() argument 1 must be an "
-                                "iterable")) == NULL)
+    fast = PySequence_Tuple(buffers_arg);
+    if (fast == NULL) {
+        PyErr_SetString(PyExc_TypeError,
+                        "recvmsg_into() argument 1 must be an iterable");
         return NULL;
-    nitems = PySequence_Fast_GET_SIZE(fast);
+    }
+    nitems = PyTuple_GET_SIZE(fast);
     if (nitems > INT_MAX) {
         PyErr_SetString(PyExc_OSError, "recvmsg_into() argument 1 is too long");
         goto finally;
@@ -4545,7 +4547,7 @@ sock_recvmsg_into(PyObject *self, PyObject *args)
         goto finally;
     }
     for (; nbufs < nitems; nbufs++) {
-        if (!PyArg_Parse(PySequence_Fast_GET_ITEM(fast, nbufs),
+        if (!PyArg_Parse(PyTuple_GET_ITEM(fast, nbufs),
                          "w*;recvmsg_into() argument 1 must be an iterable "
                          "of single-segment read-write buffers",
                          &bufs[nbufs]))
@@ -4854,14 +4856,14 @@ sock_sendmsg_iovec(PySocketSockObject *s, PyObject *data_arg,
 
     /* Fill in an iovec for each message part, and save the Py_buffer
        structs to release afterwards. */
-    data_fast = PySequence_Fast(data_arg,
-                                "sendmsg() argument 1 must be an "
-                                "iterable");
+    data_fast = PySequence_Tuple(data_arg);
     if (data_fast == NULL) {
+        PyErr_SetString(PyExc_TypeError,
+                        "sendmsg() argument 1 must be an iterable");
         goto finally;
     }
 
-    ndataparts = PySequence_Fast_GET_SIZE(data_fast);
+    ndataparts = PyTuple_GET_SIZE(data_fast);
     if (ndataparts > INT_MAX) {
         PyErr_SetString(PyExc_OSError, "sendmsg() argument 1 is too long");
         goto finally;
@@ -4883,7 +4885,7 @@ sock_sendmsg_iovec(PySocketSockObject *s, PyObject *data_arg,
         }
     }
     for (; ndatabufs < ndataparts; ndatabufs++) {
-        if (PyObject_GetBuffer(PySequence_Fast_GET_ITEM(data_fast, ndatabufs),
+        if (PyObject_GetBuffer(PyTuple_GET_ITEM(data_fast, ndatabufs),
             &databufs[ndatabufs], PyBUF_SIMPLE) < 0)
             goto finally;
         iovs[ndatabufs].iov_base = databufs[ndatabufs].buf;