Bug: CenTauRz calculation fails due to unsupported --input argument

[tctco]

Bug: CenTauRz calculation fails due to unsupported --input argument

Description

A user reported that the CenTauRz calculation fails in the 3D Slicer DCCC/PET Metric Calculator module.

When clicking the CenTauRz calculation function, an error dialog appears:

Failed to calculate CenTauRz
Error: Unknown argument: --input
usage: CentiloidCalculator [-h] [--version] [--ADNI-PET-core]
                           [--iterative] [--manual-fov-placement]
                           [--decouple VAR] inputPath outputPath image path

The error suggests that the Slicer module is passing an argument named --input, but the backend CLI currently expects positional arguments such as inputPath, outputPath, and image path.

Screenshot

The screenshot provided by the user shows the error dialog in 3D Slicer 5.6.2 when using the PET Metric Calculator module and selecting CenTauRz.

Expected behavior

The CenTauRz calculation should run normally after selecting the input PET image and output path from the Slicer module.

Actual behavior

The calculation fails immediately with:

Error: Unknown argument: --input

Possible cause

There may be a mismatch between the Slicer GUI wrapper and the CentiloidCalculator command-line interface:

• The GUI appears to pass --input
• The CLI parser expects positional arguments instead of an --input option

This may require either:

1. Updating the Slicer module to pass positional arguments correctly, or
2. Updating the CLI parser to accept --input / --output style arguments for compatibility with the GUI.

Environment

• 3D Slicer version: 5.6.2
• Module: PET Metric Calculator
• Biomarker: CenTauRz
• Platform: Windows, based on the screenshot

Additional context

The issue appears when calculating CenTauRz from the GUI. It is unclear whether the same problem also affects Centiloid or other biomarker calculations.

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Bug reported by Dr. Yulai Li @ Xiangya Hospital