I am attempting to generate a ratio of two hic matrices that are in a .mcool format at 5kb resolution. When running the command : fanc compare -S -Z -I MatrixA.mcool::/resolutions/5000 MatrixB::/resolutions/5000 comparisons/AvsB.5kb.cool, the resulting output file does not seem to be a standard cool file that can be read or processed by cooler or other similar tools.
Attempting to get additional information using cooler info comparisons/AvsB.5kb.cool results in the error: KeyError: 'No cooler found at: comparisons/ActDvsWT.5kb.cool.'
And when viewing the contents, the tree structure looks very different than a regular cool file.
$ cooler tree comparisons/ActDvsWT.5kb.cool -L 1
/
├── edges
├── expected_values
├── mask (1,) [('ix', '<i2'), ('name', 'S50'), ('description', 'S255')]
├── meta_information
└── regions
And :
$cooler tree comparisons/ActDvsWT.5kb.cool -L 2 | head
├── edges
│ ├── _i_chrpair_0_0
│ ├── _i_chrpair_0_1
│ ├── _i_chrpair_0_10
│ ├── _i_chrpair_0_11
│ ├── _i_chrpair_0_12
│ ├── _i_chrpair_0_13
│ ├── _i_chrpair_0_14
Is the output file a different filetype that needs to be somehow converted to cool?
I am attempting to generate a ratio of two hic matrices that are in a .mcool format at 5kb resolution. When running the command :
fanc compare -S -Z -I MatrixA.mcool::/resolutions/5000 MatrixB::/resolutions/5000 comparisons/AvsB.5kb.cool, the resulting output file does not seem to be a standard cool file that can be read or processed bycooleror other similar tools.Attempting to get additional information using
cooler info comparisons/AvsB.5kb.coolresults in the error:KeyError: 'No cooler found at: comparisons/ActDvsWT.5kb.cool.'And when viewing the contents, the tree structure looks very different than a regular
coolfile.And :
Is the output file a different filetype that needs to be somehow converted to cool?