Repeat expansions in Parkinson’s disease and parkinsonism across ancestries: insights from a global genetic cohort
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Last updated: May 2026
This is the online repository for the manuscript titled "Repeat expansions in Parkinson’s disease and parkinsonism across ancestries: insights from a global genetic cohort ".
Data used in the preparation of this article were obtained from the Global Parkinson’s Genetics Program (GP2; https://gp2.org).
All GP2 data are hosted in collaboration with the Accelerating Medicines Partnership in Parkinson’s disease, and are available via application on the website (https://amp-pd.org/register-for-amp-pd). For up-to-date information on GP2 data acquisition, access, and policies, visit https://gp2.org/. Tier 1 data can be accessed by completing a form on the Accelerating Medicines Partnership in Parkinson’s Disease (AMP®-PD) website (https://amp-pd.org/register-for-amp-pd). Tier 2 data access requires approval and a Data Use Agreement signed by your institution. In this analysis we used GP2 Tier 2 data from Release 8 (10.5281/zenodo.13755496) and Release 10 (10.5281/zenodo.15748014)
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analysis/directory includes all analyses discussed in the manuscript.
THIS_REPO/ ├── analyses/ | ├── 0_pathogenic_carrier_screening.ipynb | └── 1_repeat_association_plots.ipynb ├── LICENSE └── README.md
| Directory | Notebooks | Description |
|---|---|---|
analyses/ |
0_pathogenic_carrier_screening.ipynb |
Screening for pathogenic STR ranges |
analyses/ |
1_repeat_association_plots.ipynb |
Plots for association tests |
| Software | Version(s) | Resource URL | RRID | Notes |
|---|---|---|---|---|
| Python Programming Language | 3.10.13 | http://www.python.org/ | RRID:SCR_008394 | pandas; numpy; seaborn; matplotlib; Used for general data wrangling/plotting/analyses |
| R Project for Statistical Computing | 4.4.2 | http://www.r-project.org/ | RRID:SCR_001905 | tidyverse; dplyr; ggplot; patchwork; data.table; Used for general data wrangling/plotting/analyses |