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8 changes: 6 additions & 2 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -18,15 +18,19 @@ EpiSCORE is an R-package for constructing a tissue-specific DNA methylation refe

# Installation

To install:
To install (you will also need to install the dependency package presto):

```r
library(devtools)
devtools::install_github("immunogenomics/presto")
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("org.hs.eg.db")
devtools::install_github("aet21/EpiSCORE")
```

# References

Teschendorff AE, Zhu T, Breeze CE, Beck S. EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data. Genome Biology 2020 Sep 4;21(1):221. doi: 10.1186/s13059-020-02126-9 .

Zhu T, Liu J, Beck S, Pan S, Capper D, Lechner M, Thirlwell C, Breeze CE, Teschendorff AE. A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution. Nat Methods 2022 Mar;19(3):296. doi: 10.1038/s41592-022-01412-7 .
Zhu T, Liu J, Beck S, Pan S, Capper D, Lechner M, Thirlwell C, Breeze CE, Teschendorff AE. A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution. Nat Methods 2022 Mar;19(3):296. doi: 10.1038/s41592-022-01412-7 .