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predictDB_mesa_peer_pc_combos

running elastic net on mesa populations with combinations of peer factors and pcs

##Instructions: how to run elastic net combos **all data found in /home/lauren/files_for_revisions_plosgen/en_v7

  1. There are 3 directories in /en_v7/prepare_data and contain the processed data ready to use
  • **/en_v7/prepare_data/covariates
  • **/en_v7/prepare_data/expression
  • **/en_v7/prepare_data/genotypes
  1. /en_v7/new_output will contain all processed elnet files

3./en_v7/dbs will have the new db files for running models with PrediXcan

4./en_v7/model_training/scripts/ has all the scripts needed to run elastic net and generate models from mesa

  • **There are three files needed to run combos adjust these to run models accordingly
    1. mesa_pops2.txt
    2. mesa_peers.txt
    3. mesa_covars.txt
  • **adjust pop_train_combos.R to contain the correct paths to file directories (prepare_data files) *this file calls gtex_v7_nested_cv_elnet_combo.R
  • **run train_models_jobs_combo.sh *this calls pop_train_models_combo.pbs and inputs the correct variables to run models

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running elastic net on mesa populations with combinations of peer factors and pcs

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